How does this therapy for Dravet Syndrome work on a genetic level? Let's explore this ground-breaking gene therapy and understand the science behind the AAV delivery mechanism and the more complicated scientific aspects.
![3D Freelance Motion Designer Bristol UK Space Laser Cinema 4D Redshift](https://cdn.prod.website-files.com/5d41ebbceee52363a3050939/60323d40cf48e5bfe100ef39_ET_DS_LookDev_SCN1A%20DNA_v01.jpg)
The style started off a lot darker and with a focus on metalic DNA strands and minimal SSS materials, eventually this changed to a brighter scene with more harmony between the materials.
![3D Freelance Motion Designer Bristol UK Space Laser Cinema 4D Redshift](https://cdn.prod.website-files.com/5d41ebbceee52363a3050939/60323d48b7c47a13b20dbec0_ET_Neurons_v01.jpg)
The neurons were created with the X-Particles Branch system which allowed for some fantastic shapes and organic growth, but limited control for inter-neuron communication. Albert gave me a hand with the xpElectrix system that eventually took over the branching technique Check him out on Instagram at @2avisuals
![3D Freelance Motion Designer Bristol UK Space Laser Cinema 4D Redshift](https://cdn.prod.website-files.com/5d41ebbceee52363a3050939/60323d512763c673801b7244_ET_DS_AAV_v01.jpg)
I used the PDB (Protien Data Bank) to download and interpret a realistic model of aden associated viral vector serotype 9, shown here and represented slightly differently in the animation.
![3D Freelance Motion Designer Bristol UK Space Laser Cinema 4D Redshift](https://cdn.prod.website-files.com/5d41ebbceee52363a3050939/60323d555881a680e55fd528_ET_DS_%20Episome%20Scene_02_v01.jpg)
This part of the style development demonstrates the key scene of the animation where the transcription factor leaves the episome and begins its journey and transformation.